MODERN FOUNDATIONS OF QUANTUM THERAPY IN THE TREATMENT OF PSORIASIS AND OTHER DERMATOSES
Keywords:
psoriasis, dermatoses, quantum therapy, phototherapy, laser therapyAbstract
Psoriasis and other chronic dermatoses remain among the most significant problems in modern dermatology because of their recurrent course, complex pathogenesis, and considerable impact on patients’ quality of life. Conventional pharmacological therapies are often associated with systemic adverse effects, limited efficacy, and the development of resistance during long-term treatment. In recent decades, quantum therapy has emerged as a promising therapeutic direction in dermatology. Quantum therapy includes the medical application of low-intensity laser radiation, ultraviolet phototherapy, photobiomodulation, excimer laser technology, infrared radiation, and photodynamic therapy. These modalities influence cellular metabolism, immune responses, inflammatory mediators, and regenerative processes through electromagnetic energy interactions with biological tissues. Modern studies demonstrate that quantum therapy can reduce keratinocyte hyperproliferation, normalize cytokine activity, suppress chronic inflammation, and stimulate tissue repair. In psoriasis, narrow-band UVB therapy and excimer laser treatment have shown particularly high clinical effectiveness and prolonged remission rates. Quantum therapy has also demonstrated positive outcomes in atopic dermatitis, vitiligo, acne vulgaris, lichen planus, alopecia areata, and other inflammatory skin diseases. The present article reviews the modern scientific foundations of quantum therapy, its biological mechanisms, clinical applications, advantages, limitations, and future prospects in the treatment of psoriasis and other dermatoses. Special attention is paid to immunomodulatory effects, molecular mechanisms of photobiomodulation, and innovative technological developments in dermatological practice.
References
1. Griffiths CEM, Armstrong AW, Gudjonsson JE, Barker JNWN. Psoriasis. The Lancet. 2021;397(10281):1301–1315.
2. Lowes MA, Suarez-Fariñas M, Krueger JG. Immunology of psoriasis. Annual Review of Immunology. 2014;32:227–255.
3. Elmets CA, Lim HW, Stoff B, et al. Joint American Academy of Dermatology–National Psoriasis Foundation guidelines of care for the management of psoriasis with phototherapy. Journal of the American Academy of Dermatology. 2019;81(3):775–804.
4. Menter A, Strober BE, Kaplan DH, et al. Joint AAD-NPF guidelines of care for the management and treatment of psoriasis. Journal of the American Academy of Dermatology. 2020;82(1):144–164.
5. Hamblin MR. Mechanisms and applications of the anti-inflammatory effects of photobiomodulation. AIMS Biophysics. 2017;4(3):337–361.
6. Avci P, Gupta A, Sadasivam M, et al. Low-level laser therapy in skin diseases. Seminars in Cutaneous Medicine and Surgery. 2013;32(1):41–52.
7. Parrish JA, Fitzpatrick TB, Tanenbaum L, Pathak MA. Photochemotherapy of psoriasis with oral methoxsalen and longwave ultraviolet light. New England Journal of Medicine. 1974;291:1207–1211.
8. Goldinger SM, Dummer R, Schmid P, et al. Excimer laser therapy for psoriasis. Dermatology. 2006;213(2):134–139.
9. Brazzelli V, Grasso V, Fornara L, et al. Narrow-band UVB phototherapy in pediatric psoriasis. Journal of Dermatological Treatment. 2010;21(2):89–94.
10. Babilas P, Schreml S, Landthaler M, Szeimies RM. Photodynamic therapy in dermatology. European Journal of Dermatology. 2010;20(5):560–568.
