HISTOLOGY OF RENAL NEPHRONS
Keywords:
Nephron, kidney histology, glomerulusAbstract
The nephron is the fundamental structural and functional unit of the kidney, playing a crucial role in maintaining homeostasis through filtration, reabsorption, and secretion processes. This article examines the histological structure of renal nephrons, focusing on their main components, including the renal corpuscle and renal tubules. Special attention is given to the cellular organization of the glomerulus, Bowman’s capsule, proximal and distal convoluted tubules, and the loop of Henle. The study also highlights the relationship between structure and function, emphasizing how histological specialization enables efficient urine formation and regulation of body fluids. Understanding the microscopic anatomy of nephrons is essential for interpreting pathological changes in kidney diseases and improving diagnostic and therapeutic approaches in clinical practice.
References
1. Mescher, A.L. (2021). Junqueira’s Basic Histology: Text and Atlas. McGraw-Hill Education.
2. Ross, M.H., & Pawlina, W. (2020). Histology: A Text and Atlas. Wolters Kluwer.
3. Young, B., O’Dowd, G., & Woodford, P. (2014). Wheater’s Functional Histology. Elsevier.
4. Hall, J.E. (2021). Guyton and Hall Textbook of Medical Physiology. Elsevier.
5. Brenner, B.M., & Rector, F.C. (2012). The Kidney. Saunders Elsevier.
6. Kriz, W., & Kaissling, B. (2012). Structural organization of the mammalian kidney. Comprehensive Physiology.
7. Moore, K.L., Dalley, A.F., & Agur, A.M.R. (2018). Clinically Oriented Anatomy. Wolters Kluwer.
8. Standring, S. (2020). Gray’s Anatomy: The Anatomical Basis of Clinical Practice. Elsevier.
9. Tisher, C.C., & Madsen, K.M. (2011). Anatomy of the kidney. Journal of the American Society of Nephrology.
10. Kumar, V., Abbas, A.K., & Aster, J.C. (2020). Robbins & Cotran Pathologic Basis of Disease. Elsevier.
