DETERMINATION OF BIOLOGICAL AND CHRONOLOGICAL AGE IN CHILDREN

Authors

  • Zebo Xudoyqulova Termez University of Economics and Service, Faculty of Medicine Lecturer, Department of Medical Clinical Sciences
  • Jasur Saidov Termez University of Economics and Service, Faculty of Medicine Lecturer, Department of Medical Clinical Sciences
  • Laziza Choriyeva Student, Faculty of Medicine Termez University of Economics and Service, Termez, Uzbekistan

Keywords:

biological age, chronological age, child development, growth assessment, skeletal maturity

Abstract

Assessment of biological and chronological age is an essential component of pediatric
health evaluation, providing valuable information about a child's growth, maturation, and
developmental status. While chronological age is determined by the date of birth, biological age
reflects the actual physiological and functional maturity of the organism. Differences between these
indicators may reveal growth disorders, endocrine abnormalities, nutritional deficiencies, or
developmental delays. This article examines the principles, methods, and clinical significance of
determining biological and chronological age in children. Particular attention is given to
anthropometric measurements, skeletal maturity assessment, dental development, and secondary
sexual characteristics as reliable markers of biological age. Understanding the relationship between
biological and chronological age contributes to accurate diagnosis, individualized healthcare, and
effective monitoring of child development

References

1. Tanner J.M. Growth at Adolescence. 2nd ed. Oxford: Blackwell Scientific Publications, 1962.

2. Greulich W.W., Pyle S.I. Radiographic Atlas of Skeletal Development of the Hand and Wrist.

Stanford University Press, 1959.

3. Cameron N., Bogin B. Human Growth and Development. 3rd ed. Academic Press, 2012.

4. Rogol A.D., Clark P.A., Roemmich J.N. Growth and pubertal development in children and

adolescents. Endocrinology and Metabolism Clinics of North America. 2002;31(3):573–593.

5. Malina R.M., Bouchard C., Bar-Or O. Growth, Maturation, and Physical Activity. Human

Kinetics, 2004.

6. Demirjian A., Goldstein H., Tanner J.M. A new system of dental age assessment. Human

Biology. 1973;45(2):211–227.

7. WHO Multicentre Growth Reference Study Group. WHO Child Growth Standards. Geneva:

World Health Organization, 2006.

8. Behrman R.E., Kliegman R.M., Jenson H.B. Nelson Textbook of Pediatrics. 21st ed. Philadelphia:

Elsevier, 2020.

9. Marshall W.A., Tanner J.M. Variations in the pattern of pubertal changes in boys and girls.

Archives of Disease in Childhood. 1970;45(239):13–23.

10. Hermanussen M., Wit J.M. How much nutrition for how much growth? Hormone Research in

Paediatrics. 2017;88(2):138–145.

Downloads

Published

2026-09-20