THE IMPACT OF VITAMIN D DEFICIENCY ON THE SKELETAL AND REPRODUCTIVE SYSTEMS IN WOMEN
Keywords:
vitamin D deficiency, osteoporosis, reproductive healthAbstract
Vitamin D deficiency is a widespread global health problem, particularly among women of reproductive age. It plays a critical role not only in calcium homeostasis and bone metabolism but also in reproductive health through its influence on hormonal regulation, ovarian function, and immune modulation. Deficiency of vitamin D has been associated with osteoporosis, increased fracture risk, menstrual irregularities, infertility, and conditions such as polycystic ovary syndrome (PCOS) and endometriosis. This article aims to evaluate the effects of vitamin D deficiency on the skeletal and reproductive systems in women, highlighting underlying mechanisms, clinical implications, and management strategies. The findings emphasize the importance of early screening and adequate supplementation.
References
1. World Health Organization (2022). Vitamin D deficiency report.
2. Holick MF. (2007). Vitamin D deficiency. New England Journal of Medicine.
3. Rosen CJ et al. (2012). Vitamin D and bone health.
4. Lerchbaum E, Obermayer-Pietsch B. (2012). Vitamin D and fertility. European Journal of Endocrinology
5. Muscogiuri G et al. (2017). Vitamin D and PCOS.
6. Palacios C, Gonzalez L. (2014). Vitamin D worldwide status.
7. Bischoff-Ferrari HA. (2005). Vitamin D and fractures.
8. Aghajafari F et al. (2013). Vitamin D and pregnancy.
9. NIH (2021). Vitamin D guidelines
10. Endocrine Society (2011). Clinical practice guideline
