LABOR ANALGESIA AND UTEROTONIC DRUGS IN MODERN OBSTETRICS: BALANCING PAIN RELIEF, MATERNAL CHOICE AND HEMORRHAGE PREVENTION

Authors

  • Mustafo Xurramov Student of General Medicine, Faculty of Medicine, Termiz University of Economics and Service
  • Islom Jo'rayev Student of General Medicine, Faculty of Medicine, Termiz University of Economics and Service
  • Zarina Tillyayeva Teacher, Faculty of Medicine, Termez University of Economics and Service

Keywords:

labor analgesia, epidural analgesia, opioids, uterotonics, oxytocin

Abstract

Background: Safe childbirth requires both humane pain relief and effective prevention of
postpartum hemorrhage. Objective: This article examines labor analgesia and uterotonic drugs as
complementary components of intrapartum and postpartum care. Methods: WHO recommendations,
ACOG guidance and postpartum hemorrhage evidence were reviewed. Results: Epidural, opioid,
relaxation and manual techniques are recognized options for labor pain relief depending on
preference and context; uterotonics, especially oxytocin where appropriate, reduce hemorrhage risk.
Discussion: The main clinical challenge is not choosing between comfort and safety, but integrating
informed consent, monitoring and timely action. Conclusion: Pain relief and uterotonic prevention
should be taught together as parts of respectful, evidence-based maternity care

References

1. World Health Organization. WHO recommendations: intrapartum care for a positive

childbirth experience. Geneva: WHO; 2018.

2. World Health Organization. WHO recommendations: uterotonics for the prevention of

postpartum haemorrhage. 2018 update. Geneva: WHO; 2018.

3. World Health Organization. Postpartum haemorrhage: maternal and perinatal health. 2023.

https://www.who.int/teams/sexual-and-reproductive-health-and-research/areas-of-work/maternaland-

perinatal-health/postpartum-haemorrhage

4. Begum F, et al. FIGO recommendations on objective measurement of blood loss after

birth for early detection of postpartum hemorrhage. International Journal of Gynecology and

Obstetrics. 2025.

5. American College of Obstetricians and Gynecologists. Approaches to Limit Intervention

During Labor and Birth. Committee Opinion No. 766. Obstetrics & Gynecology. 2019.

6. World Health Organization. Maternal mortality. Fact sheet, updated 7 April 2025.

https://www.who.int/news-room/fact-sheets/detail/maternal-mortality

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Published

2026-09-19