Application of Modern Biopolymer-Based Biomaterials in Endodontic and Restorative Dentistry: A Clinical and Experimental Analysis
Keywords:
biopolymers, biomaterials, endodontics, restorative dentistry, regenerative dentistryAbstract
The rapid development of biomaterial science has significantly influenced modern dental practice
by introducing biopolymer-based materials capable of enhancing tissue regeneration, improving
biocompatibility, and optimizing clinical outcomes. Unlike conventional restorative materials,
contemporary biopolymers possess biological properties that actively support healing processes
while minimizing inflammatory responses. This review analyzes the clinical and experimental
applications of natural and synthetic biopolymer-based biomaterials in endodontic and restorative
dentistry. Particular attention is given to collagen, chitosan, hyaluronic acid, alginate, gelatin, silk
fibroin, and biodegradable polymer composites that have demonstrated promising regenerative
potential. Recent experimental studies indicate that these biomaterials improve pulp tissue
regeneration, dentin repair, antimicrobial activity, and adhesive performance while maintaining
favorable physicochemical characteristics. Furthermore, advances in nanotechnology, tissue
engineering, and three-dimensional bioprinting have expanded the therapeutic possibilities of
biopolymer-based scaffolds for personalized dental treatment. The available evidence suggests that
modern biopolymers represent an important step toward biologically oriented dentistry by
combining structural support with regenerative capacity. Continued interdisciplinary research is
expected to further improve the clinical effectiveness and long-term performance of these
biomaterials.
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