KALAMUSH GORMONLARINING EKSPERIMENTAL TIREOTOKSIKOZDA VA AN`ANAVIY HAMDA NOAN`ANAVIY DAVOLASHDAN KEYINGI O’ZGARISHLARI
Abstract
Qalqonsimon bez gormonlari ko'p fiziologik faoliyatda muhim rol o'ynaydi, shu jumladan hayvonlarning reproduktiv funksiyasi to'g'ri ishlashida, ularning rivojlanishini nazorat qilishda qatnashadi. Qalqonsimon bez gormonlarining ortiqchaligi yoki etishmasligi moyaklar funksiyasining o'zgarishiga olib keladi. Tireotoksikoz modeli chaqirilgan kalamushlarni va ularni an`anaviy hamda noan`anaviy davolashda gormonlarni qanday o’zgarishga uchrashi aniqlandi. kalamushlarda testosteron va qalqonsimon bez gormonlarining eksperimental tireotoksikozi hamda an`anaviy va noan`anaviy davo ko’rsatkichlari tahlil qilinganda birinchi tajriba (tireotoksikoz chaqirilgan) hayvonlari nazorat guruh kalamushlarga nisbatan qonidagi TTG miqdori keskin hamda erkin testosteron miqdori bir necha marotaba kamaydi, lekin qondagi T4 darajasi va erkin T4 darajasi oshdi. Merkazolil va zaytun moyi bilan davolangan kalamushlar merkazolil bilan davolangan guruh hayvonlari bilan solishtirilganda qonida TTG miqdori va erkin testosteron miqdori birmuncha ko’paydi, aksincha, qondagi T4 miqdori hamda erkin T4 miqdori kamaydi.
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